Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A broad-spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.

Etymologies

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Examples

  • In fact, the following fluoroquinolones are either under use restriction, or have been removed from the market: (1) temafloxacin due to red blood cell damage, kidney failure and hypoglycemia; (2) grepafloxacin because of heart problems; and (3) trovafloxacin due to liver damage.

    Tequin's Serious Injuries - Bristol-Myers Feigns Ignorance 2006

  • Trovan, the brand name given by Pfizer to trovafloxacin, is from the quinolone family of antibiotics.

    The Guardian World News Sarah Boseley 2010

  • Maisikeli, 63, who campaigns for families involved in Pfizer's trovafloxacin trial, lost two daughters, Fatahiyya, then 17, and Surayya, who was six.

    The Guardian World News Sarah Boseley 2010

  • The families allege that Pfizer conducted the study of its experimental drug trovafloxacin (Trovan) without obtaining informed consent

    BMJ Latest Articles 2009

  • He subsequently joined Pfizer, Inc., as a clinical researcher, becoming extensively involved in the clinical development of the antibiotics azithromycin (Zithromax®) and trovafloxacin (Trovan®) and the use of these medicines in treatments for typhoid fever and sexually transmitted diseases.

    News & Events from Dartmouth 2009

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