Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
enzyme -inhibitingantibiotic , used as an experimental tool inbiology .
Etymologies
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Examples
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Co-treatment of the γ-secretase reporter cells with PBA blocked the repressive effects of tunicamycin and thapsigargin upon APP proteolysis, UPR activation, and apoptosis.
Elites TV PLoS ONE 2010
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Three unrelated pharmacological agents (tunicamycin, thapsigargin and brefeldin A) all repressed APP proteolysis in parallel with activation of unfolded protein response (UPR) signaling-a biochemical marker of ER stress.
Elites TV PLoS ONE 2010
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CHMFs subjected to tunicamycin or thapsigargin, compounds that inhibit protein glycosylation and disrupt ER calcium levels respectively inducing ER stress, also showed an increase in MstnPP expression (in addition to ER stress marker proteins GRP78 and Herp), possibly due to the activation of NF-κB
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Three unrelated pharmacological agents (tunicamycin, thapsigargin and brefeldin A) all repressed APP proteolysis in parallel with activation of unfolded protein response (UPR) signaling-a biochemical marker of ER stress.
Elites TV 2010
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Co-treatment of the γ-secretase reporter cells with PBA blocked the repressive effects of tunicamycin and thapsigargin upon APP proteolysis, UPR activation, and apoptosis.
Elites TV 2010
-
CHMFs subjected to tunicamycin or thapsigargin, compounds that inhibit protein glycosylation and disrupt ER calcium levels respectively inducing ER stress, also showed an increase in MstnPP expression (in addition to ER stress marker proteins GRP78 and Herp), possibly due to the activation of NF-κB
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Conversely, the hypersensitivity of lrk-1 mutant animals to the endoplasmic reticulum stressor tunicamycin was reduced in
Journal of Biological Chemistry current issue Samann, J., Hegermann, J., von Gromoff, E., Eimer, 2009
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As a positive control, tunicamycin, a chemical inducer of ER stress also showed increased IFNAR1 phosphorylation.
PLoS ONE Alerts: New Articles Rinki Minakshi et al. 2009
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Biosynthesis of an unglycosylated envelope glycoprotein of Rous sarcoma virus in the presence of tunicamycin
xml's Blinklist.com 2008
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