Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A process in which the viral capsid of a virus is removed, leading to the release of the viral genomic nucleic acid.

Etymologies

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Examples

  • Boll W, Griffin AM, Kirchhausen T (2006) A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating.

    PLoS ONE Alerts: New Articles

  • Vhs is also present in the tegument and thus immediately functional following virion uncoating de novo synthesized vhs is thought to be partially compromised as a result of its association with another viral protein, VP16

    PLoS ONE Alerts: New Articles

  • Upper right, virus particle enters cell followed by uncoating and release of positive-stranded HCV RNA genome.

    PhysOrg.com - latest science and technology news stories

  • (ER) by regulating the uncoating of coat protein I (COPI) - coated vesicles.

    Journal of Biological Chemistry current issue

  • Stremlau M, Perron M, Lee M, Li Y, Song B, et al. (2006) Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5

    PLoS ONE Alerts: New Articles

  • Although researchers still do not know precisely what triggers the uncoating of VP7, they do know that it appears to happen when the virus senses a lowered concentration of calcium in its environment.

    HHMI News

  • "Normally, calcium creates a bridge between VP7 molecules that holds them in place until uncoating," he said.

    HHMI News

  • "Our structure revealed that the antibody makes an additional bridge, cementing the subunits together, making the virus resistant to the uncoating trigger and preventing it from infecting cells."

    HHMI News

  • "And it is the loss of VP7 in the uncoating step that triggers VP4 to carry out its task."

    HHMI News

  • They used RNAi screening technology to selectively turn off more than 19,000 human genes to determine which human factors facilitate viral entry, uncoating, nuclear import, viral replication and other necessary functions of the virus.

    The Times of India

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