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Previous studies have suggested that the reduction or absence of REP1 could have a variable effect on the prenylation of Rabs and therefore could affect different aspects of the trafficking in the RPE and other cell types We hypothesized that underprenylation of certain Rabs would probably influence the pH level in lysosomes, and exocytosis/secretion of cells.
PLoS ONE Alerts: New Articles Natalia V. Strunnikova et al. 2009
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