from The Century Dictionary.

  • Relating to only one of the parents.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective From but one parent.


Sorry, no etymologies found.


  • The combined measurement of both allelic ratios and normalized intensities provides enhanced detectability of aberrations and allows identification of copy-neutral genetic anomalies, such as uniparental disomy and mitotic recombination.

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  • We can diagnose numerous single gene disorders, both dominant and recessive, as well as cases of uniparental disomy.

    Cytogenomics Lab

  • We can also determine parent of origin for deletions and uniparental disomy.

    Cytogenomics Lab

  • Recent advances in genome-wide single-nucleotide polymorphism (SNP) analyses have revealed previously unrecognized microdeletions and uniparental disomy (UPD) in a broad spectrum of human cancers.

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  • This hypothesis is substantiated by new findings of complex chromosomal imbalances involving not only whole chromosomal aneuploidies and uniparental disomies but also segmental deletions, duplications, and amplifications in human cleavage-stage Scheme for the development of somatic CNV mosaicism.

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  • Leinonen R, Lindgren CM, Kivinen K, Dahlman-Wright K, et al. (2005) Global analysis of uniparental disomy using high density genotyping arrays.

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  • The number of annotated copy number neutral LOHs (or uniparental disomies (UPDs)) was 211, with a median length of 235 kb and coverage of 10 Mb per cell line.

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  • The frequencies of different subtypes in PWS are usually given in literature as 70 maternal uniparental disomy (mUPD) and 3-5% others (imprinting centre (IC) defects and translocations).

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  • In addition, SNP arrays can identify copy number neutral aberrations showing LOH, such as gene conversions and uniparental isodisomies.

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  • In contrast, PDP-FISH has been reported for three CNV loci using fosmid probes, which distinguish signal presence and absence rather than signal intensity differences pod-FISH has already been successfully used to identify the parental origin of individual derivative chromosomes, such as the characterization of chimerism and uniparental disomy 15

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