from Wiktionary, Creative Commons Attribution/Share-Alike License

  • v. Simple past tense and past participle of up-regulate.


Sorry, no etymologies found.


  • This well-conserved gene, whose ancestors are over 450 million years old (found in fish and chicken), isabundantly present in feeding-related nuclei of the mammalian brainstem and hypothalamus, where it is significantly up-regulated after 48-h of food deprivation.

    Dr. Sharma’s Obesity Notes » Blog Archive » Is FTO the Junk-Food Gene?

  • Trichinella spiralis: Vascular endothelial growth factor is up-regulated within the nurse cell during the early phase of its formation.

    Parasite Rex

  •   We found that many disease-promoting genes (including those associated with cancer, heart disease, and inflammation) were down-regulated or "turned off," whereas protective, disease-preventing genes were up-regulated or "turned on."

    Changing Your Lifestyle Can Change Your Genes

  •   Another gene that suppresses tumor formation called SFRP was up-regulated, thereby reducing the risk of cancer.

    Changing Your Lifestyle Can Change Your Genes

  • They adjust themselves in various ways, and genes are up-regulated or down-regulated, depending.

    Treydte, Moberg, Soon and Baliunas « Climate Audit

  • LRP1 is also up-regulated in many tumors, therefore once in the brain, GRN1005 may gain entry into tumor cells using the same receptor by a process known as endocytosis.

    Reuters: Press Release

  • The IL1RAP receptor has also been shown to be up-regulated on stem cells of AML and ALL.

    Reuters: Press Release

  • Meanwhile, proteins involved in cell death (apoptosis) were up-regulated, as were many proteins related to fat metabolism, changes that might be related to narrowing or hardening of blood vessels.


  • Quantitative RT-PCR analysis indicated that five defense-related genes, ghAOX1, hin1, npr1, ghdhg-OMT, and hsr203J, were up-regulated in T-34 inoculated with V. dahliae.

    BioMed Central - Latest articles

  • Besides the relevance of proteins as targets, a recent study has also shown that miR-155 was up-regulated during the treatment with TNF - in RASFs [17].

    PLoS ONE Alerts: New Articles


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