from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The epithelium of the urinary bladder
Sorry, no etymologies found.
The team is currently studying how the urothelium, the main cell type that covers the luminal surface of the bladder, forms a highly effective barrier, and how bacteria cause urinary tract infection (UTI).
"Dr. Sun and his multidisciplinary team are uniquely poised to address key questions regarding the structure and function of the bladder urothelium," said Chris Mullins, PhD, director of Basic Cell Biology Programs, Division of Kidney, Urologic and Hematologic
Now, the same group has looked at urothelium in BPS/IC patients.
Increased immunoreactivity for HIP/PAP was frequently observed in the umbrella cells of the urothelium in IC patients, suggesting that expression of HIP/PAP is induced in the urothelium and then released into the urine of IC patients.
Dr. Tetsuya Makino and colleagues from Osaka, Japan have demonstrated in a rat cyclophosamide cystitis model that PAP III is expressed in the urothelium of the bladder and PAP I was expressed in the primary afferent neurons of dorsal root ganglia that innervate the bladder.
Building on this work, the team analyzed 15 paired samples of bladder cancer and nearby urothelium for AURKA overexpression.