Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of many organic compounds having a vanillyl-based structure

Etymologies

Sorry, no etymologies found.

Examples

  • He wanted to find a way to block the keyhole, which is called transient potential vanilloid 1 or TRPV1.

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  • The co-carcinogenic effect of capsaicin appears to be mediated through the epidermal growth factor receptor (EGFR) and not the transient receptor potential vanilloid subfamily member 1 (TRPV1), a known pain receptor.

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  • It stimulates the transient receptor potential vanilloid 1 receptors, or TRPV1, which when persistently stimulated desensitive neurons responsible for transmitting pain.

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  • What is hot in peppers is capsaicin, a chemical that elicits a sensation of pain when it bind the vanilloid receptors in the nerve endings

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  • Capsaicin is a selective agonist of the transient receptor potential vanilloid 1 receptors (TRPV1).

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  • This new NGF inhibitor complements Abbott's robust early-stage pipeline of candidates in development for chronic pain, which spans multiple mechanisms, including vanilloid cellular receptors (TRPV1), cannabinoid receptors (CB2), Histamine H3 receptors and preclinical work on a number of promising ion channel targets.

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  • The transient receptor potential vanilloid receptor 1 (TRPV1) gene has been associated with pain perception, and genetic variations in TRPV1 may modify the presence and phenotype of chronic pancreatitis.

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  • In addition, Evotec has a number of proprietary projects in preclinical development as well as a worldwide license agreement with Pfizer to research, develop and commercialize small molecule vanilloid receptor

    News

  • In addition, Evotec has worldwide collaboration and license agreements with Pfizer to research, develop and commercialize small molecule vanilloid receptor (VR1) antagonists.

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  • Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, et al. (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors.

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