Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A muscarinic acetylcholine receptor agonist with reasonable selectivity for the M1 and M4 subtypes, possibly useful in treating Alzheimer's disease and schizophrenia.

Etymologies

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Examples

  • Whereas, all ligands induced loss of cell surface receptor binding, no intracellular vesicles could be observed after treatment with AC-260584 or xanomeline.

    BioMed Central - Latest articles

  • Brief stimulation of M1 receptors with AC-260584 or xanomeline resulted in persistent activation of M1 receptors, suggesting that continual receptor signaling might impede or delay receptor endocytosis into intracellular vesicles.

    BioMed Central - Latest articles

  • Brief stimulation of M1 receptors with AC-260584 or xanomeline resulted in persistent activation of M1 receptors, suggesting that continual receptor signaling might impede or delay receptor endocytosis into intracellular vesicles.

    BioMed Central - Latest articles

  • The orthosteric agonists carbachol, oxotremorine-M and pilocarpine were compared to the allosteric agonists AC-42, AC-260584, N-desmethylclozapine and xanomeline.

    BioMed Central - Latest articles

  • Whereas, all ligands induced loss of cell surface receptor binding, no intracellular vesicles could be observed after treatment with AC-260584 or xanomeline.

    BioMed Central - Latest articles

  • The orthosteric agonists carbachol, oxotremorine-M and pilocarpine were compared to the allosteric agonists AC-42, AC-260584, N-desmethylclozapine and xanomeline.

    BioMed Central - Latest articles

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