from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
analgesic drugused for the ameliorationof severeand chronic pain.
Sorry, no etymologies found.
In 2000, just when he was ready to give up on finding relief, Pearson's doctor told him about a clinical trial for a new drug called ziconotide (brand name: Prialt).
These are calcium channels that are on nerves that conduct pain signals, and it's a validated central nervous system target in that there is an existing medication called Prialt ziconotide, which is only available for direct injection into the brain, that blocks these receptors.
It developed Prialt (ziconotide), a non-opioid pain killer that blocks N-type calcium channels.
It took a quarter of a century to produce a synthetic version of the compound, which serves as the basis of the new drug Prialt ziconotide.
The only conotoxin-derived drug approved for human use is ziconotide.
Cone shells contain therapeutically useful peptides including the conotoxins, and one such peptide, ziconotide, has been approved.
Apparently, the same data on Elan's pain medication Prialt (ziconotide) was published twice.