from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
nucleoside analog reverse transcriptase inhibitor, a type of antiretroviral drug, the first approved treatment for HIV.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow
from The American Heritage® Dictionary of the English Language, 4th Edition
AZT is "toxic" … year … nobody calls zidovudine "AZT" since 1980s, except for AIDS-dissidents.
Some countries - notably South Africa - are loath to buy or distribute low-cost drugs, such as zidovudine and nevirapine, that have been shown to slash the risk of mother-to-child transmission through birth or breast-feeding by up to two-thirds.
Like the earliest anti-HIV drugs such as zidovudine (AZT), introduced 10 years earlier, these block enzymes vital for viral multiplication.
Therefore countries should progressively phase out the use of stavudine as a preferred first-line therapy option and move to less toxic alternatives such as zidovudine (AZT) or tenofovir (TDF), WHO recommended.
The WHO recommended "that countries progressively phase out the use of stavudine as a preferred first-line therapy option and move to less toxic alternatives such as zidovudine
Among the new discounts announced Monday is a $66-a-year price for a combination treatment for children based on zidovudine, a staple of AIDS treatment.
Treatment options include a one-month course of zidovudine (AZT) during the last weeks of pregnancy or a single dose of nevirapine during delivery followed by a single dose to the infant within 72 hours of birth.
Expectant mothers were also treated with a cocktail of zidovudine and didanosine from week 36 of their pregnancies until one week after delivery.
Combivir made by Britain's GlaxoSmithKline PLC contains lamivudine and zidovudine.
Both groups also took a short course of a fourth drug, zidovudine, better known as AZT.
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