from The American Heritage® Dictionary of the English Language, 4th Edition
- n. See proenzyme.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A proenzyme, or enzyme precursor, which requires a biochemical change (i.e. hydrolysis) to become an active form of the enzyme.
from the GNU version of the Collaborative International Dictionary of English
- n. A mother substance, or antecedent, of an enzyme or chemical ferment; -- applied to such substances as, not being themselves actual ferments, may by internal changes give rise to a ferment.
from The Century Dictionary and Cyclopedia
- n. A substance from which an enzym may be formed by internal change. Also zymogene.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active
Sorry, no etymologies found.
Trypsin itself then cleaves lysine peptide bonds, and so, once a small amount of trypsin is generated, it participates in cleavage of its own zymogen, generating – more trypsin!
Redman, David Sabatini and Yutaka Tashiro; it led to the characterization of the zymogen granules and to the discovery of the segregation of secretory products in the cisternal space of the endoplasmic reticulum.
It may very likely produce the same change in the membrane that is caused by the entrance of the spermatozoon under normal circumstances -- membrane formation may be necessarily coincident with the liberation in the egg of some zymose which arises from a pre-existent zymogen.
Protein C is a serine protease blood coagulation factor that circulates as an inactive zymogen and is activated by thrombin during blood coagulation to form activated protein C APC.
This prodomain maintained MMP-2 as a zymogen and this loop is cleaved by MMP-14 after MMP-2 secretion given active form.
In such a model, cells secrete MMP-2 as an inactive zymogen (Pro-MMP-2) containing 8 disulphide bonds
This enzyme contains an amino-terminal signal sequence (Pre) that directs it to the secretory pathway via the endoplasmic reticulum (ER) and a propeptide (Pro) that maintains it as inactive zymogen
Vande Haar penned a 12-verse epic in which he manages to rhyme words like "phospholipids," "hemorrhage" and "zymogen."
As of this typing, it contains 13 scrolling screens of active netlabels (OK, I'm on a netbook; your scrolling may vary), from the Guadalajara, México-based zymogen.net (plus a bunch whose monikers start with numbers or symbols).
The loss of vacuole acidification in V-ATPase mutants prevents zymogen activation and causes defects in the proteolytic function of the vacuole