from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A chronic disease of adults marked by enlargement of the bones of the extremities, face, and jaw that is caused by overactivity of the pituitary gland.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland.

from the GNU version of the Collaborative International Dictionary of English

  • n. Chronic enlargement of the extremities and face.

from The Century Dictionary and Cyclopedia

  • n. A disease characterized by hypertrophy of the bones and soft tissues of the face and extremities.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor)


from The American Heritage® Dictionary of the English Language, 4th Edition

French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see acro-) + Greek megas, megal-, big; see meg- in Indo-European roots.

from Wiktionary, Creative Commons Attribution/Share-Alike License

French acromégalie, from New Latin acromegalia, from Ancient Greek ἄκρον (akron, "tip, extremity") and μέγας (megas, "large"). acro- + -megaly


  • It is possible that in acromegaly, in some stages of the disease there may be a hypophyseal diabetes and at others a metahypophyseal diabetes.

    Bernardo Houssay - Nobel Lecture

  • The frequency of glycosuria or diabetes in acromegaly has been reported many times; Atkinson found it in

    Bernardo Houssay - Nobel Lecture

  • In the disease called acromegaly, which is due to a change in the pituitary gland, amongst other things are noted ` ` melancholic tendencies, loss of memory and mental and physical torpor. ''

    The Foundations of Personality

  • This parallelled his true situation, where he had a normal face until being exposed to poison gas during WWI, which triggered the onset of the head-enlarging syndrome known as acromegaly.

    Dr. Franklin Ruehl, Ph.D.: Intriguing Factoids From the Horror/Sci-Fi/Mystery Genre

  • Hatton died with his last picture, 1946's THE BRUTE MAN, still awaiting release -- the victim of a bone-distorting pituitary disease called acromegaly, which had also been responsible for his distorted features.

    Fred Lightner: Another Rondo Hatton?

  • They should note what happens in the disease called acromegaly, a condition of too much growth hormone.

    Baseball and Growth Hormones: Big Muscles, Big Bodies, Big Trouble

  • I wonder if Kerry suffered from a mild case of the pituitary problem called acromegaly that causes bones to keep growing.

    Archive 2005-06-05

  • The result of this condition, which is called acromegaly (ak'roh-meg'uh-lee; "large extremities" G), is a rather grotesque distortion of features.

    The Human Brain

  • Enlargement of the hypophysis and of the cavity of the sella turcica are found in the rare disease acromegaly, which is characterized by gradual enlargement of the face, hands, and feet, with headache and often a peculiar type of blindness.

    XI. Splanchnology. 4d. The Hypophysis Cerebri

  • And of course there's a disease, acromegaly, which is actually characterized by an excess of human growth hormone.

    NPR Topics: News


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