from The American Heritage® Dictionary of the English Language, 4th Edition
- transitive v. Physiology To draw inward toward the median axis of the body or toward an adjacent part or limb.
- n. Chemistry A chemical compound that forms from the addition of two or more substances.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- v. To draw towards a center or a middle line.
- n. The product of an addition reaction
from the GNU version of the Collaborative International Dictionary of English
- transitive v. To draw towards a common center or a middle line.
from The Century Dictionary and Cyclopedia
- To draw on; induce; allure.
- In physiology, to bring to or toward a median line or main axis. See adduction, 2.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- v. draw a limb towards the body
- n. a compound formed by an addition reaction
At that time Alex was studying the role of mono-ubiquitination of histones (for the histone-ubiquitin adduct H2A known also as protein A24 or uH2A, see above).
These researchers reported that at the non-permissive temperature, the cell lost the histone H2A-ubiquitin adduct.
These bases can be chemically modified in a number of ways, including by alkylation, in which an alkyl group (or "adduct") is transferred onto a guanine base.
With extraordinary effort I can move my right hand a little and can adduct my left arm some six inches across my chest.
DNA radioactivity was essentially in a single different adduct base, different from the normal bases present in DNA.
In that case CH3O2 reacts with NO2 to form an adduct CH3O2NO2 .
The adduct "stores" CH3O2, but the bond between the CH3O2 and the NO2 moities a convenient way of designating the molecular units is weak, and collisions can break it, thus the tight loop.
It takes the masses from CE-MS and compares to an in-house metabolite database, and of course takes into account common adduct products and isotopes.
Researchers speculate that this results when ellagic acid forms adduct (from Latin, “drawn toward”) with DNA, thus masking binding sites to be occupied by the carcinogens.
This information on the ubiquitin-histone adduct along with the striking similarities we found between APF-1 and ubiquitin in their general characteristics such as molecular mass and amino acid composition, led Keith Wilkinson and his colleague Arthur (Art) Haas who were post-doctoral fellows in the laboratory of Ernie, along with Michael Urban from Zweidler's laboratory, to carry out a series of direct experiments, showing unequivocally that APF-1 is indeed ubiquitin.