Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A drug, C5H4N4O, used to treat gout because it inhibits the synthesis of uric acid.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A drug used primarily to treat hyperuricemia and its complications.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a drug (trade name Zyloprim) used to treat gout and other conditions in which there is an excessive buildup of uric acid

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[allo– + purin(e) + –ol.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

allo- + purine + -ol

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Examples

  • Patients can take drugs, particularly one called allopurinol, to reduce the level of uric acid and eventually eliminate symptoms of gout.

    news | TL | http://www.tuscaloosanews.com 2008

  • Despite afflicting an estimated two to six million Americans, the standard approach for treating gout over the last 40 years has been a drug called allopurinol, which inhibits an enzyme that produces uric acid.

    News from The Scientist 2010

  • He said metformin, unlike the recalled allopurinol, does not contain cornstarch, which could be the breeding ground for the fungus mucorales.

    unknown title 2009

  • For many years, the most common drug used to treat gout was allopurinol, which is generally safe and effective, but has been known to cause life-threatening rashes in rare cases.

    Medlogs - Recent stories 2008

  • Or your doctor may suggest another drug, such as allopurinol (Zyloprim) or hydrochlorothiazide (Esidrix, Hydro-DIURIL), that prevents stones in other ways.

    Q&A: Does lemonade help prevent kidney stones? 2010

  • Or your doctor may suggest another drug, such as allopurinol (Zyloprim) or hydrochlorothiazide (Esidrix, Hydro-DIURIL), that prevents stones in other ways.

    Q&A: Does lemonade help prevent kidney stones? 2010

  • Azathioprine, a drug that prevents rejection of transplanted organs and allopurinol which is used in the treatment of gout were developed in 1957 and 1963, respectively.

    Physiology or Medicine 1988 - Press Release 1988

  • He said studies have shown that increasing the dose of a drug such as allopurinol does not have a great impact on serum urate, but by combining allopurinol with drugs such as benzbromarone, a greater reduction in urate levels can be achieved.

    Medicaid and Medicare 2010

  • Besides a low purine diet, preventive medicines such as allopurinol, febuxostat, and probenecid can be used to prevent recurrences.

    The Daily Times News Headlines 2010

  • In addition, because increasing the excretion of serum uric acid is additive to the effects of drugs such as allopurinol that decrease the production of uric acid, RDEA594 in combination with such drugs has the potential to treat the significant portion of the gout population that is not adequately treated with existing therapies.

    Ardea Biosciences Announces Positive Results for RDEA594 in Combination with Febuxostat or Allopurinol in Gout Patients - Yahoo! Finance 2010

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