from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Methotrexate.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Methotrexate
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
Freireich finally approached Zubrod with his idea: “I wanted to treat them with full doses of vincristine and amethopterin, combined with the 6-MP and prednisone.”
The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.