from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A yellow hygroscopic powder, C12H12As2N2O2·2HCl·2H2O, formerly used to treat syphilis, yaws, and other spirochetal infections.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A phenolic amine derivative of arsenic that was used to treat syphilis (under the trade name of Salvarsan).


ars(enic) + phen(yl) + amine.
(American Heritage® Dictionary of the English Language, Fourth Edition)
From arsenic + phen- + amine. (Wiktionary)


  • As one reads the reports of writers who have given arsphenamine in large doses and in rapidly repeated courses of treatment, and when one hears of the remissions obtained, in number and in duration far superior to the number of remissions observable in untreated paralysis, it cannot confidently be maintained that arsphenamine is ineffective against progressive paralysis.

    Julius Wagner-Jauregg - Nobel Lecture

  • In 1909 Ehrlich and Hata finally achieved success with the 606th experimental compound, patented under the name "Salvarsan" and later known as arsphenamine; in modified form, the drug remained the mainstay of syphilis treatment until the discovery of penicillin.


  • Additionally, as previously mentioned, in 1909, the German scientist Paul Ehrlich discovered arsphenamine, a drug that was marketed under the name of salvarsan.

    Syphilis from 1880 to 1920: A Public Health Nightmare and the First Challenge to Medical Ethics

  • Malaria therapy, along with the use of arsphenamine drugs, became the dominant treatment of paresis.

    The Mad Among Us

  • Yet it seems indeed, disregarding rare exceptions, that sooner or later a point is reached where arsphenamine treatment is unable to halt the fatal progression.

    Julius Wagner-Jauregg - Nobel Lecture

  • The discovery of arsphenamine (Salvarsan) by Ehrlich brought new hope.

    Julius Wagner-Jauregg - Nobel Lecture

  • It is due to the late Kyrle of Vienna that the malaria treatment was extended to these luetics in that in these cases, which are not yet immediately threatened, he prescribed a course of arsphenamine to precede the malaria, and a second course to follow it.

    Julius Wagner-Jauregg - Nobel Lecture

  • Afterwards, this treatment was carried out systematically and with an increasing dose of tuberculin (up to 1.0), and simultaneously a vigorous iodine-and-mercury treatment, later accompanied by arsphenamine injections, was also introduced.

    Julius Wagner-Jauregg - Nobel Lecture

  • In 1915 he was first to use arsphenamine for the treatment of

    Citizendium, the Citizens' Compendium - Recent changes [en]

  • In 1915 he was first to use arsphenamine for the treatment of syphilis of the eye.

    Citizendium, the Citizens' Compendium - Recent changes [en]


Log in or sign up to get involved in the conversation. It's quick and easy.