from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun pathology An abnormal increase in the number of
astrocytesdue to the destruction of nearby neurons
Sorry, no etymologies found.
Some neuronal loss and reactive astrocytosis with kuru plaques, Congo-red positive, as seen in cerebellar sections.
The researchers solved this problem by using a virus to selectively cause reactive astrocytosis without triggering broader inflammation and brain injury, in a mouse model.
Full flow cytometry details and machine settings are described in the Online Figure 6: Anti-CD40L treatment decreases astrocytosis and microgliosis while reducing motor neuron loss in the spinal cord of
The researchers focused on an abnormal condition called reactive astrocytosis, known to occur in many neurological diseases.
The current study found that reactive astrocytosis reduces the supply of that enzyme, which in turn decreases inhibition and allows neurons to fire out of control.
The impact of reactive astrocytosis on brain function is difficult to investigate because it usually occurs in the context of brain inflammation and abnormal changes in surrounding cells.
Hadberg H, Thomsen P, Moos T (2000) The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease.