Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun pathology An abnormal increase in the number of
astrocytes due to the destruction of nearbyneurons
Etymologies
Sorry, no etymologies found.
Examples
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Some neuronal loss and reactive astrocytosis with kuru plaques, Congo-red positive, as seen in cerebellar sections.
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The researchers solved this problem by using a virus to selectively cause reactive astrocytosis without triggering broader inflammation and brain injury, in a mouse model.
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Full flow cytometry details and machine settings are described in the Online Figure 6: Anti-CD40L treatment decreases astrocytosis and microgliosis while reducing motor neuron loss in the spinal cord of
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The researchers focused on an abnormal condition called reactive astrocytosis, known to occur in many neurological diseases.
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The current study found that reactive astrocytosis reduces the supply of that enzyme, which in turn decreases inhibition and allows neurons to fire out of control.
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The impact of reactive astrocytosis on brain function is difficult to investigate because it usually occurs in the context of brain inflammation and abnormal changes in surrounding cells.
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Hadberg H, Thomsen P, Moos T (2000) The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease.
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