Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun pathology An abnormal increase in the number of astrocytes due to the destruction of nearby neurons

Etymologies

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Examples

  • G, Ohlemeyer C, et al. (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue.

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  • Matyash M, Pivneva T, Schipke CG, Ohlemeyer C, et al. (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue.

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  • While astrogliosis and NG2 deposition are not limited to sections containing the injury epicenter, in the absence of a visible injury epicenter, the widespread expression of both proteins along the spinal cord makes the analysis of these parameters challenging.

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  • In the following sections, we discuss the effect of engrafted hCNS-SCns in relationship to lesion volume, tissue sparing, serotonergic fiber sprouting/regeneration, NG2 deposition, astrogliosis, and angiogenesis.

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  • While we did not observe any changes in deposition of the scar-associated NG2 proteoglycan as a result of cell transplantation, the possibility that engrafted cells modified the physical component of astrogliosis remained unclear.

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  • These findings suggest that neither hCNS-SCns nor hFb alter astrogliosis when compared to vehicle control.

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  • 2007 Adenosine dysfunction in astrogliosis: causes for seizure generation.

    The Other Brain

  • Both gray and white matter structures were severely atrophic with nearly total loss of neurons and replacement of the neuropil with prominent gemistocytic astrogliosis (

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  • The cerebral cortex is markedly disrupted with prominent astrogliosis and presence of amyloid plaques (arrows in

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  • Fig. 12D) (Pearson r: r = 0.01, p = 0.98, 2-tailed t-test); as well, no significant correlations between hFb engraftment and GFAP-positive astrogliosis (

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