Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An organism, such as a strain of bacteria, that has lost the ability to synthesize certain substances required for its growth and metabolism as the result of mutational changes.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Any microorganism that has lost the ability to synthesize an organic compound required for its growth, usually as a result of mutation

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Back-formation from auxotrophic.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

auxo- + -troph

Examples

  • We are seeking a candidate interested in understanding transport and function of cholesterol in the sterol-auxotroph organism Caenorhabditis elegans.

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  • Pechous RD, McCarthy TR, Mohapatra NP, Soni S, Penoske RM, et al. (2008) A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge.

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  • From this strain we generated a Ura − auxotroph (strain SCMSP202) by plating on solid media containing 5-Fluoroorotic Acid (5-FOA).

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