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dedifferentiation

Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. Biology Regression of a specialized cell or tissue to a simpler, more embryonic, unspecialized form. Dedifferentiation may occur before the regeneration of appendages in plants and certain animals and in the development of some cancers.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The loss or reversal of differentiation.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. the loss of specialization in form or function

Etymologies

de- +‎ differentiation (Wiktionary)

Examples

  • War, from this point of view, is a precondition for development along new lines of necessity, and the dedifferentiation is the first stage of

    Introduction to the Science of Sociology

  • Another promising approach involves reprogramming adult cells to revert back to an embryonic state, a process known as " dedifferentiation ."

    Stem-Cell Finesse Too Grotesque

  • If we consider the Disease Evolution Table, we can see pain results from inflammation, impregnation, degeneration and dedifferentiation phases.

    Dr. Richard Palmquist: Taking the Sting Out of Pain for Your Pet

  • If modern societies, for classical social theory, were characterized by differentiation, for Baudrillard, postmodern societies are characterized by dedifferentiation, the "collapse" of (the power of) distinctions, or implosion.

    Jean Baudrillard

  • While the genes were active during maximum dedifferentiation activity, she said, so much is going on in cells after a newt's forelimb is cut off that it's difficult to pick out specific dedifferentiation genes.

    Cells That Go Back in Time

  • Tsilfidis and her colleagues are now trying to pinpoint which genes are responsible for kick-starting newt dedifferentiation.

    Cells That Go Back in Time

  • The creature's cells can regenerate thanks to built-in time machines that revert cells to early versions of themselves in a process called dedifferentiation.

    Cells That Go Back in Time

  • But at least one religious leader believes the ability to use dedifferentiation to create human stem cells would eliminate the controversy.

    Cells That Go Back in Time

  • "For those of us who want to understand what happens in dedifferentiation, our ultimate goal is to be able to form a pool of stem-cell-like cells that would be able to repopulate the organ or tissue you're trying to repair," said Catherine Tsilfidis , a scientist at the Ottawa Health Research Institute who has reproduced Keating's findings, which she describes as "beautiful."

    Cells That Go Back in Time

  • "Whether (those genes) can actually induce dedifferentiation is yet to be determined," Tsilfidis said.

    Cells That Go Back in Time

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