Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A calcium channel blocker drug, C22H26N2O4S, that acts as a coronary vasodilator and is used in the form of its hydrochloride to treat angina pectoris and hypertension.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A benzothiazepine drug, a potent vasodilator used to treat hypertension, migraine, angina pectoris, and some types of arrhythmia.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a calcium blocker (trade name Cardizem) used in treating hypertension or angina or heart failure

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[(vaso)dil(ator) + -tiazem, suff. for calcium channel blockers (shortening and alteration of benzothiazepine, class of compounds : benzo– + thi(o)– + az(o)– + ep(oxide) + –ine).]

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Examples

  • Non-dihydropyridine calcium-channel blockers, such as diltiazem, have been shown to have antiproteinuric and renoprotective properties. 2 Since more than 50\% of the patients

    New England Journal of Medicine 2008

  • Calcium channel blockers such as nifedipine (Procardia) and diltiazem (Cardizem) interfere with the chemical change that enables sperm to penetrate the egg.

    A Baby at Last! Mark L. Fuerst 2010

  • All calcium blockers, such as nifedipine (Procardia) and diltiazem (Cardizem)

    A Baby at Last! Mark L. Fuerst 2010

  • It can also interact with a long list of drugs, including lovastatin (Altoprev, Mevacor, and generic), clarithromycin (Biaxin and generic), and diltiazem (Cardizem and generic).

    Echinacea anti-cold claims hugely overrated 2010

  • For example, the brand-name drug Cardizem, a calcium channel blocker, was no more effective than its generic version, diltiazem.

    Generic drugs are as good as brand names for heart problems 2008

  • For example, the brand-name drug Cardizem, a calcium channel blocker, was no more effective than its generic version, diltiazem.

    Generic drugs are as good as brand names for heart problems 2008

  • Use REYATAZ with caution in patients with preexisting conduction system disease or when administered with other drugs that may prolong the PR interval including beta-blockers other than atenolol, diltiazem, verapamil, and digoxin, especially drugs metabolized by CYP3A.

    unknown title 2011

  • Doctors will traditionally order any number of drugs from their pharmaceutical arsenal, including digoxin, the blood thinner warfarin, calcium channel blockers (like diltiazem or nifedipine), beta blockers (like propranolol, sotalol or metoprolol) or anti-arrhythmic drugs like propafenone, procainamide, disopyramide or amiodarone.

    The Full Feed from HuffingtonPost.com R.Ph. Suzy Cohen 2011

  • When used with REYATAZ, a 50% dose reduction of diltiazem should be considered, and ECG monitoring is recommended.

    unknown title 2011

  • In the new study, the researchers revealed how the widely available prescription drugs diltiazem, verapamil, and in some cases dantrolene, acted on cells from patients with Gaucher's disease.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2010

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