from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A tricyclic antidepressant drug, C9H21NO, used in its hydrochloride form.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A psychotropic agent with tricyclic antidepressant and anxiolytic properties.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)


from The American Heritage® Dictionary of the English Language, 4th Edition

[d(ibenz)oxepin(e), tricyclic structural component : di– + benz– + oxepin(e), seven-member ring with one oxygen atom (ox(o)– + (h)ep(ta)– + –ine).]


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  • Yet he'd felt a real sadness — the sadness of consummation— hearing a subject who'd struggled for years with anxiety, suicidal guilt, and religious zeal tell him, after the successful tuning of his doxepin dosages, "Doctor, I'm just not sure what I was so upset about, all that time.

    --Richard Powers, 2007, The Echo Maker, p. 190

    November 7, 2008