from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics, medicine The ability of a portion of a genome to be targeted by a drug, especially by a small molecule drug


Sorry, no etymologies found.


  • Potential areas of study for the future are proposed, which include a new classification system consisting of specific families and the identification of PPI targets with high druggability potential based on key descriptors of the interaction.

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  • However, it should be noted that this type of analysis represents an initial step, since the druggability of each site requires evaluation by medicinal chemists

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  • Coleman RG, Smyth KT, Cao Q, Soulard P, et al. (2007) Structure-based maximal affinity model predicts small-molecule druggability.

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  • 2P2I database stores structural information about PPIs with known inhibitors and provides a useful tool for biologists to assess the potential druggability of their interfaces.

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