Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Describing the ability of a portion of a genome to be targeted by a drug, especially by a small molecule drug.

Etymologies

from Wiktionary, Creative Commons Attribution/Share-Alike License

drug +‎ -able

Examples

  • PCMP will employ state-of-the art technology to generate a detailed profile of key "druggable" or otherwise "actionable" cancer genomic alterations in a

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  • Glutamatergic systems are also implicated by identification of "druggable" metabotropic 7, GRIK2 kainate and GRIA4 AMPA glutamate receptors, as well as several cell adhesion molecules that are associated with classical synapses.

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  • The current screen assayed the effect of over 7,000 individual gene knockdowns, representing the "druggable" genome, on brostallicin response.

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  • It is thought that these molecules will represent a set of "druggable" targets.

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  • It is thought that these molecules will represent a set of 'druggable' targets.

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  • Potentially any disease-causing gene, cell type or tissue can be targeted with RNAi, including those not 'druggable' with small molecules or protein-based therapies.

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  • "Our goal is to get to the part of the protein channel which is easily 'druggable' ― that is an effective target for drugs.

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  • "It opens up a whole new area of research to find which proteins are 'druggable'.

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  • Kinases, fortuitously, possess at least one such deep druggable pocket.

    The Emperor of All Maladies

  • Researchers will focus on creating drug treatments for several important genes known as “druggable targets.”

    Scientists Identify Genes Linked to Crohn���s Disease

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