Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun An interaction between nonallelic genes in which the genotype at one locus affects the expression of alleles at another locus.
  • noun A film that forms over the surface of a urine specimen.
  • noun The suppression of a bodily discharge or secretion.

from The Century Dictionary.

  • noun A substance swimming on the surface of urine: opposed to hypostasis, or sediment.
  • noun An arrested or stationary condition in the ancestral history of a group of organisms.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics The modification of the expression of a gene by another unrelated one

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun the suppression of a gene by the effect of an unrelated gene

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[Greek, stoppage, from epistanai, to stop, check : ep-, epi-, epi- + histanai, to place; see stā- in Indo-European roots.]

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Examples

  • These genetic interactions, termed epistasis, can impact all aspects of organisms and play

    PhysOrg.com - latest science and technology news stories 2010

  • There is "epistasis," which means that some gene variants behave differently depending on what variants of other genes are present, but this changes the outcome little in practice.

    The Failed Promise of Genomics Matt Ridley 2010

  • IC systems have components that exihibit this kind of epistasis, they exhibit numerous interdependencies.

    Death of a popular anti-ID argument 2007

  • Yet, at least at the individual level, nature's contribution cannot be quantified; too many parts of the equation, such as epistasis, or the process whereby one gene suppresses the expression of another, elude measurement.

    How We Become What We Are 1994

  • Yet, at least at the individual level, nature's contribution cannot be quantified; too many parts of the equation, such as epistasis, or the process whereby one gene suppresses the expression of another, elude measurement.

    How We Become What We Are 1994

  • Whitlock & Bourguet, Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations among fitness components, Evolution 2000

    2009 November - Telic Thoughts 2009

  • Nachman argues a "fix" is "synergistic epistasis", but I hope to show (with lots of help from Walter ReMine and others), this won't fix the problem.

    The Weasel Thread 2009

  • Do you think that no real scientist has ever considered the effects of pleiotropy and epistasis?

    It's more than genes, it's networks and systems - The Panda's Thumb 2010

  • Leaving aside the plain fact that "unselected" mutations regularly persist due to drift, epistasis, "hitchhiking" with selected mutations, etc., let's edit your sentence to make it accurate: "If Behe is right, then a double CCC will never happen ALL AT ONCE."

    Behe's Test, Take 2 2008

  • Leaving aside the plain fact that "unselected" mutations regularly persist due to drift, epistasis, "hitchhiking" with selected mutations, etc., let's edit your sentence to make it accurate: "If Behe is right, then a double CCC will never happen ALL AT ONCE."

    Behe's Test, Take 2 2008

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