epistatic

Guts: Again, my understanding is that changes to amino acid sequence are immensely context-dependent (i.e. their effect depends extensively on which other mutations are already present, or epistatic interactions) and only very small number of selectively important trajectories are likely to exist to high-fitness proteins.

The Weasel Thread

Again, my understanding is that changes to amino acid sequence are immensely context-dependent (i.e. their effect depends extensively on which other mutations are already present, or epistatic interactions) and only very small number of selectively important trajectories are likely to exist to high-fitness proteins.

The Weasel Thread

That would depend on the actual degree of interbreeding, along with mutation rate, population size, epistatic interactions, etc.

"Intraspecific macroevolution" within domestic dog breeds - The Panda's Thumb

Professor Flegr has mentioned also pleiotropy and epistatic interactions mentioned in PZMyers article using layman words.

It's more than genes, it's networks and systems - The Panda's Thumb

One of the experimenters concluded that changes to amino acid sequence are immensely context-dependent (i.e. their effect depends extensively on which other mutations are already present, epistatic interactions), and why a only very small number of selectively important trajectories are likely to exist to high-fitness proteins.

Death of a popular anti-ID argument

His key observations of abundant epistatic effects among mutations is just another way of observing that the genetic variability of a trait is under genetic control.

Darwin and neutrality - The Panda's Thumb

We propose that the genotype-phenotype map can evolve by two main routes: epistatic mutations, or the creation of new genes.

Darwin and neutrality - The Panda's Thumb

Homozygous recessive at the epistatic locus and, wa-la, no expression of the W/M locus…

The genetics of Harry Potter? - The Panda's Thumb

Whenever allele frequencies of its epistatic partner change, either by drift or selection, the A allele's selective effect also changes and, like the case of G ×

Evolutionary Genetics

We used Bayesian model selection to comprehensively map main, epistatic and sex-specific QTL in an F2 reciprocal intercross between two chicken lines divergently selected for high or low growth rate.

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