Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A statin, C24H25FNO4·Na, that blocks the body's synthesis of cholesterol and is administered especially to individuals who are at risk for heart disease.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A drug of the statin class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun least expensive statin drug (trade name Lescol); usually taken orally at bedtime

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[flu(oro)– + -vastatin, statin suff.; see pravastatin.]

Examples

  • Patients who were initially randomized to fluvastatin or placebo in the 5 - to 6-year trial were offered open-label fluvastatin in a 2-year extension of the original study.

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  • Previous data suggest that lipophilic statins such as fluvastatin and N-bisphosphonates such as zoledronic acid, both inhibitors of the mevalonate metabolic pathway, have anti-cancer effects in vitro and in patients.

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  • A study from Japan using a cell culture assay system reported that inteferon plus fluvastatin inhibited hepatitis C virus more effectively than did inteferon plus ribaviran.

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  • A study from Japan using a cell culture assay system reported that inteferon plus fluvastatin inhibited hepatitis C virus more effectively than did inteferon plus ribaviran.

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  • After a mean follow-up of 5.1 years, fluvastatin lowered LDL cholesterol concentrations by 32%.

    Archive 2003-06-01

  • Risk reduction with fluvastatin for the primary endpoint [a heart attack, fatal or nonfatal - ss] ... was not significant, although there were fewer cardiac deaths or non-fatal MI ... in the fluvastatin group than in the placebo group.

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  • Although cardiac deaths and non-fatal MI seemed to be reduced, fluvastatin did not generally reduce rates of coronary intervention procedures or mortality.

    Archive 2003-06-01

  • Overall effects of fluvastatin were similar to those of statins in other populations.

    Archive 2003-06-01

  • Although cardiac deaths and non-fatal MI seemed to be reduced, fluvastatin did not generally reduce rates of coronary intervention procedures or mortality.

    Medpundit

  • After a mean follow-up of 5.1 years, fluvastatin lowered LDL cholesterol concentrations by 32%.

    Medpundit

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