Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Any of a class of lipid-lowering drugs that reduce serum cholesterol levels by inhibiting a key enzyme involved in the biosynthesis of cholesterol.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun pharmacology Any of a class of drugs (chiefly lactones or pyrroles) that lower the amount of cholesterol in the blood by inhibiting an enzyme involved in its biosynthesis.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[From the names of such lipid-lowering drugs as pravastatin.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

From the suffix -statin, from terms such as lovastatin and simvastatin.

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Examples

  • It may be that someone who has had muscle pain from a statin is at a higher risk of muscle pain from ezetimibe, but there is currently no information about that.

    Archive 2007-03-01 Steve Carper 2007

  • It may be that someone who has had muscle pain from a statin is at a higher risk of muscle pain from ezetimibe, but there is currently no information about that.

    Lactose-Free Statins Steve Carper 2007

  • A controversial study showing that the blockbuster cholesterol-lowering drug Vytorin failed to slow the buildup of artery plaques more than a cheaper statin is certain to provoke questions among heart patients taking Vytorin or its sister drug Zetia.

    What you should know about Vytorin and Zetia 2008

  • According to the New England Journal of Medicine, boosting HDL cholesterol with extended-release niacin (Niaspan) is a more effective way of slowing atherosclerosis in high-risk patients on long-term statin therapy than seeking additional LDL cholesterol reductions by adding ezetimibe.

    Do latest studies show niacin may work better than prescription drugs at lowering cholesterol? 2009

  • In fact, long-term statin use appears unlikely to substantially increase or decrease overall cancer risk, the researchers noted.

    Yahoo! News: Business - Opinion 2010

  • For example, odds for endometrial tumors fell by 39 percent among long-term statin users, while the risk for melanoma dropped by 19 percent, the study found.

    Yahoo! News: Business - Opinion 2010

  • Long-term statin use 'reduces risk of gallstones requiring surgery'

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ani 2010

  • But the new 10-year study suggests that "even long-term statin use is unlikely to increase the risk of common cancers," according to lead researcher Eric J. Jacobs, strategic director of pharmacoepidemiology at the American Cancer Society.

    Yahoo! News: Business - Opinion 2010

  • "In the last few years, a number of publications in medical journals have reported apparent symptoms of anxiety and major depression in patients upon long-term statin administration," says Amitabha Chattopadhyay at the Centre for Cellular and Molecular Biology in

    The Times of India 2010

  • In fact, long-term statin use appears unlikely to substantially increase or decrease overall cancer risk, the researchers noted.

    Yahoo! News: Business - Opinion 2010

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