Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A small molecule that reacts with a specific antibody but cannot induce the formation of antibodies unless bound to a carrier protein or other large antigenic molecule.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun immunology Any small
molecule that can elicit animmune response only when attached to a largecarrier such as aprotein .
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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I made the observation that random bred animals immunized with antigens with restricted heterogeneity, such as hapten conjugates of poly L-lysine distribute themselves into two groups, responders and nonresponders.
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To overcome that, Dr. Janda attaches a hapten - which is either a bit of the drug itself, or a synthetic version of it - to a larger protein that acts as a platform.
NYT > Home Page By DOUGLAS QUENQUA 2011
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Carrier proteins such as DT stimulate T-helper cells which co-operate with B-cells to enable them to respond to the hapten by providing accessory signals.
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First of all, the method does not work with just any antibodies, it works with antibodies to a particular hapten (a β-diketone).
fbharjo commented on the word hapten
It just hapten. I had to latch on to it!?
July 2, 2011