Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry The state of being fully
phosphorylated , so that all potential phosphorylation sites are occupied
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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GSK3 adds phosphate to tau protein and "hyperphosphorylation" of tau protein causes it to tangle.
The Full Feed from HuffingtonPost.com Scott Mendelson, M.D. 2009
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The next step will be to identify drug compounds that can negate the effects of the three kinases linked to tau hyperphosphorylation.
Die Trying Child, Lee 1998
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These findings, the results of a multi-year TGen study, are published in this month's edition of BMC Genomics in a paper titled: High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation.
Die Trying Child, Lee 1998
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Of these 26, three of them -- EIF2AK2, DYRK1A and AKAP13 -- were found to cause hyperphosphorylation of tau, permanently dismantling the microtubule bridges.
Die Trying Child, Lee 1998
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Overexpression of GSK-3 leads to hyperphosphorylation of the tau protein, an anomaly which occurs in a number of neurodegenerative diseases known collectively as tauopathies, which include Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP) and Pick disease.
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Overexpression of GSK-3 leads to hyperphosphorylation of the tau protein, an anomaly which occurs in a number of neurodegenerative diseases known collectively as tauopathies, which include Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP) and Pick disease.
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GSK3B also phosphoryklates tau but does not induce hyperphosphorylation in response to calpain activating stimuli.
WN.com - Articles related to DTI favors zero tariffs on cement, wheat 2010
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Overexpression of GSK-3 leads to hyperphosphorylation of the tau protein, an anomaly which occurs in a number of neurodegenerative diseases known collectively as tauopathies, which include Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP) and Pick disease.
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GSK3B also phosphoryklates tau but does not induce hyperphosphorylation in response to calpain activating stimuli.
WN.com - Articles related to DTI favors zero tariffs on cement, wheat 2010
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GSK3B also phosphoryklates tau but does not induce hyperphosphorylation in response to calpain activating stimuli.
WN.com - Articles related to DTI favors zero tariffs on cement, wheat 2010
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