from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. An isoenzyme.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An isoenzyme.


from The American Heritage® Dictionary of the English Language, 4th Edition

iso- + (en)zyme.


  • The findings add to an accumulation of evidence suggesting that inhibition of the cytochrome P450 2D6 isozyme (CYP2D6) may adversely affect outcomes in breast cancer patients taking tamoxifen. - medical news plus CME for physicians

  • Click on an or generic/brand variant to breath for judgement about the isozyme in our database.


  • -- (BUSINESS WIRE) -- Apr 8, 2009 - KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced the Company has initiated a third Phase 2a study of KAI-1678, a first-in-class, isozyme-selective, small peptide inhibitor of the epsilon protein kinase C pathway (epsilon PKC).


  • Lindsley CW, Zhao Z, Leister WH, Robinson RG, Barnett SF, et al. (2005) Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

    PLoS Biology: New Articles

  • Liao YF, Kudo S, Eto S, Mattei MG, et al. (1995) Molecular cloning and expression of cDNAs encoding human alpha-mannosidase II and a previously unrecognized alpha-mannosidase IIx isozyme.

    PLoS ONE Alerts: New Articles

  • Fox EA, Strydom DJ, Riordan JF (1989) Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial ACE.

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  • NSAIDs may reduce pain and inflammation following injury by inhibiting COX isozyme-induced prostaglandin synthesis; however, as they circulate within the body indiscriminately, rather than localizing to the source of an athlete's specific aches and pains, they may produce undesirable side effects.

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  • Our results suggest that low CYP 2C isozyme activity is a common property of drugs, whereas other isozymes, such as CYP 2D6, show little discrimination between drugs and unoptimized compounds found in screening libraries.

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  • We observed cross-library isozyme inhibition (30-78%) with important differences between libraries.

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  • Tramadol undergoes hepatic metabolism via the cytochrome P450 isozyme CYP2D6, being O - and N-demethylated to five different metabolites.

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  • are enzymes that differ in amino acid sequence but catalyze the same chemical reaction

    February 18, 2011