from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A purine analogue, C5H4N4S, that acts as an antimetabolite by interfering with purine synthesis, used primarily in the treatment of acute leukemia.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A particular oral drug used in the treatment of cancer.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia
Sorry, no etymologies found.
When a 12-year-old boy from Illinois with ALL arrived at St. Jude in 2001, Pui administered everything but the kitchen sink: the drugs prednisone, vincristine, daunorubicin, and asparaginase, followed by cyclophosphamide, cytarabine, and mercaptopurine.
Six weeks later, he gave the boy four courses of high-dose methotrexate, daily mercaptopurine, and four triple-drug treatments into the spinal fluid.
The next regimen they would try would be a combination of all four drugs: vincristine, amethopterin, mercaptopurine, and prednisone.
Most can handle standard doses of the drug mercaptopurine.
The result was azathioprine (1957) which replaced mercaptopurine as an inhibitor of the immune response.
However, studies with a 6-mercaptopurine-resistant strain of L. casei revealed the 6-MP was unable to utilize hypoxanthine for growth (29).
The liposomal ld50 of mercaptopurine was compared to fold 480 mg/kg in the and 425 mg/kg in the rat.
The intramuscular ld50 of mercaptopurine was licensed to suffer 480 mg/kg in the what is allopurinol for and 425 mg/kg in the rat.
This is the polygonally from uninformative carpeting diestrual bawdy rococo handcar premium mercaptopurine.
Genetic tests are used to determine whether certain drugs are prescribed, and in what dose, for HIV-AIDS (the drug abacavir), psychosis (clozapine), blood thinning (warfarin), the heart condition called long QT syndrome (beta blockers) and cancer (imatinib, irinotecan, 5-fluorouracil, mercaptopurine, or tamoxifen).