from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. That part of the mesoderm of an embryo that develops into connective tissue, bone, cartilage, etc.

from The Century Dictionary and Cyclopedia

  • n. The tissue or substance of the mesoderm of some animals, as sponges.
  • n. In embryology, the whole or a portion of the middle germ-layer, or mesoblast, when this layer is not epithelial, but consists of stellate, loosely interconnected, or even disconnected cells like those seen in primitive forms of connective tissue.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. mesodermal tissue that forms connective tissue and blood and smooth muscles


mes(o)- + -enchyma.
(American Heritage® Dictionary of the English Language, Fourth Edition)


  • This secreted tissue in its simple or in its differentiated state, with all its derivatives, we call the mesenchyme "

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  • In recent years, however, pluripotent stem cells were discovered in various human tissues – in the spinal cord, in the brain, in the mesenchyme (connective tissue) of various organs, and in the blood of the umbilical cord.

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  • They distinguished in the middle layer two quite distinct elements, the mesoblast proper, formed by the evagination of the walls of the archenteron, and the mesenchyme, formed by free cells budded off from the germ-layers.

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  • Embryonic cells, which become singly detached from their epitheliar connections we consider to be something quite different from the germ-layers, and accordingly we call them by the special name of mesenchyme germs or primary cells of the mesenchyme.

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  • Di-Poi N, Ng CY, Tan NS, Yang Z, Hemmings BA, et al. (2005) Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.

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  • Orotates are taken up by tissues that embryonically from mesenchyme: bone, cartilage, liver, blood vessels, heart and the blood brain barrier

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  • Bovine SOLD1 is expressed in trophoblast mononucleate cells (TMCs) and is localized in the cotyledonary mesenchyme.

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  • Beginning as a hemocytoblast, a cell that has multiple development potentials, in the mesenchyme, the structure slowly turns into an erythroblast, which then loses its nucleus and mitochondria and gains hemoglobin.


  • Raldh2 is also expressed in the mouse dorsal pancreatic mesenchyme at the early stage of pancreas specification until E12. 5

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  • The inner layer of epithelial cells of the murine urogenital sinus starts invading the outer layer of mesenchyme to form the ducts of the prostate gland after E16.

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