from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Producing myosis, or contraction of the pupil of the eye.
- n. An agent that produces myosis.
from the GNU version of the Collaborative International Dictionary of English
- adj. Producing myosis, or contraction of the pupil of the eye, as opium, calabar bean, etc.
from The Century Dictionary and Cyclopedia
- Pertaining to or causing myosis, or contraction of the pupil.
- n. A drug which causes myosis.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a drug that causes miosis (constriction of the pupil of the eye)
- adj. of or relating to or causing constriction of the pupil of the eye
Sorry, no etymologies found.
The great trouble with myotic treatment is not its lack of efficiency, but the difficulty of carrying it out successfully on ambulant patients, even in the better walks of life.
We must wait now for a sufficient period of time and then compare the value of myotic treatment with that of operations by means of which satisfactory filtration is produced.
We do not usually compare the statistics of early aseptic days with those of the pre-antiseptic period, and I do not think we ought to compare the statistics of myotic treatment with ordinary iridectomy any longer, but that we should wait until we can make a comparison between the results of prolonged myosis and those of an improved modern technic which establishes a permanent filtration.
The substance isophysostigmin, found with eserin in Calabar bean, according to Ogiu, exceeds in its myotic activity the sulphate of eserin, _i.e. _, 1/80 of a grain of the drug is equal to 1/60 of a grain of the sulphate of eserin, but it is certainly not less irritating than physostigmin, and according to Stephenson's researches, is more so, and in this sense has no superiority over the usual alkaloid.
It has always been easy to attribute the myotic action of these drugs, or at least, of eserin, to their stimulant action on the peripheral ends of the oculo-motor, thus causing sphincter contraction, and to a depressing action on the sympathetic fibers, thus causing removal of the action of the dilatator of the iris.
This is not the place to introduce a discussion of the comparative value of iridectomy and myotic treatment in simple glaucoma as based upon statistical records.
Doubtless many patients with chronic glaucoma can be satisfactorily managed with myotic treatment, although personally I have always advocated operation when this could be performed, but it cannot always be performed.
Many authors, for example, Darier, Grandclement and others, are strong in their recommendation of adrenalin, particularly if this drug is added to the various myotic mixtures, and yet adrenalin is certainly not without danger in the treatment of glaucoma.
There is a good deal of clinical evidence to indicate that in this type of glaucoma, as well as in the so-called sub-acute varieties, myotic activity is increased by a mixture of pilocarpin and eserin in the same solution, exactly as a mixture of arecalin and eserin is more potent than either of the drugs in separate solution.
The failure in myotic power of the heart and in the muscles of respiration through reflex influence of par vagum and great sympathetic nerves, whereby pulmonary circulation is impeded, are among the earliest of phenomena.