from The American Heritage® Dictionary of the English Language, 4th Edition
- n. An embryonic cell from which a nerve cell develops.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. The embryonic cell that develops into a nerve cell
from The Century Dictionary and Cyclopedia
- n. An embryonic cell:
- n. One of two large cells or teloblasts which are situated at the posterior end of the body in the annelid embryo and larva and give rise to the ventral nerve-cord of the adult animal.
- n. One of the cells in the embryonic brain and spinal cord of vertebrates. These cells are said to give rise without division to the ganglion-cells.
- n. In arthropod embryos, certain ectodermal cells which proliferate inward from the surface to form rows of elements that become the ganglion-cells.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a cell from which a nerve cell develops
The differentiation of specific nerve cell types in the thoracic segments results from spatial and temporal control of neuroblast lineages via an interplay of Hox, Pbx/Meis, and temporal genes.
In the most anterior segments, which make up the fly brain, neuroblast division continued long enough to make Ap clusters, but nonetheless the clusters didn't form.
Ap cluster neurons form at the end of a long series of neuroblast cell divisions and only in the presence of specific molecular signals.
Here, they found that neuroblast cells in the abdomen stopped dividing before reaching the stage that would create Ap clusters.
A group of powerful pattern-generating genes called the bithorax complex, which is able to turn cell division off, is expressed at the proper time in the abdomen, and so, the authors tested its role in terminating abdominal neuroblast division.
Morphological analysis of vector control and APP cells showed neuroblast-like morphology with differentiated perikaria (arrows) and occasional short neurites (arrowheads).
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate.
But neuroblast growth can sometimes spin out of control and become a brain tumor.
Similarly, vector control as well as APP cells conserved their neuroblast-like morphology with differentiated perikaria and short neurites after treatment with GBE (