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  • A type of difficult Pokemon playthrough challenge (2010 to present) where if a Pokemon faints, it must be removed from the team. And also, only one Pokemon (the first one encountered) can be caught in each area. A web comic that originated this challenge idea had an drawing of the Pokemon Nuzleaf crossed with the character Locke from the TV show LOST.

    https://knowyourmeme.com/memes/the-nuzlocke-challenge

    June 11, 2026