Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Of or pertaining to an osteoblast

from The Century Dictionary and Cyclopedia

  • Of or pertaining to osteoblasts; having the character of an osteoblast: as, osteoblastic cells; an osteoblastic process.

Etymologies

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Examples

  • Bafico A, Dai J, Aaronson SA, Keller ET (2005) Prostate cancer cells promote osteoblastic bone metastases through Wnts. Cancer Res 65: 7554-7560.

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  • As well as it speeds up bone repair as it works with the stimulation which is offered by the fibroblastic and osteoblastic

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  • Most recently, analysis of mice engineered to express DKK1 in the osteoblastic HSC niche, indicated that the self-renewal of HSCs is negatively affected when Wnt signaling is inhibited by DKK1

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  • Hofbauer LC, Lacey DL, Dunstan CR, Spelsberg TC, Riggs BL, Khosla S. Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells.

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  • TNF, one of the more potent osteoclastogenic cytokines produced during rheumatoid inflammation, is able to induce RANKL expression on the surface of stromal-osteoblastic cells, directly or by promoting IL-1 secretion (104, 105).

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  • Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption.

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  • RANKL, also known as osteoclast differentiation factor (ODF), tumor necrosis factor - related activation-induced cytokine (TRANCE) and osteoprotegerin ligand, is a member of the TNF ligand family (106) produced in osteoblastic lineage cells and activated T cells

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  • The first indications about a possible implication of this system in RA pathogenesis came with the observation that proinflammatory cytokines such as TNF and IL-1 are able to upregulate RANKL expression in human osteoblastic cells in vitro (113).

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  • Microarray analysis showed that, compared with an osteoblastic cell line, the expression of 653 genes was changed more than 2 folds in three osteosarcoma cell lines.

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  • - An osteoblastic (and osteoclastic) induced excretion of pain mediators that result in sensitization of the nociceptor. [prostaglandin E, bradykinin, histamine, and interleukin]

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