Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Of or relating to
ribosomes .
Etymologies
Sorry, no etymologies found.
Examples
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"Molecular signatures of ribosomal evolution," PNAS 105 (2008): 13953-58.
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One can agree that LGT will likely not interfere with a robust phylogeny for primates that indeed recreates ancient splittings of their populations, without buying in to the notion that the supposed sisterhood of Thermotogales and Aquificales [two bacterial phyla — OT] revealed by a small subset of their shared ribosomal protein genes reflects an even remotely similar evolutionary process.
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Thomas Steitz's high resolution structures of the large ribosomal subunit in functional complexes led to atomic level understanding of how formation of peptide bonds between amino acids is catalysed on the ribosome.
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This assembly maps involves 15 universal small subunit ribosomal proteins, and of these 15, ten have a moonlighting role (we shall explore several of these functions at a future date).
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Venkatraman Ramakrishnan's crystal structures of the small ribosomal subunit in functional complexes led to atomic level understanding of how ribosome-assisted reading of the genetic code can be so accurate that virtually all proteins are made error free in accordance with the blueprints of their genes.
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Ramakrishnan, Steitz and Yonath determined high resolution structures of ribosomal subunits in complex with antibiotic drugs, leading to atomic level understanding of how these drugs inhibit ribosome function and how drug target resistance may evolve.
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Ada Yonath's pioneering work during the 1980s laid the foundation for determination of high-resolution ribosomal structures with crystallographic techniques.
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When a messenger RNA has found a ribosome, it is anchored between the ribosomal subunits, ready to be translated to the chain of amino acids which, properly folded, becomes active protein.
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In 1998 Thomas Steitz solved the so called phase problem for the large ribosomal subunit and could thereby determine the first ribosomal crystal structure.
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In the year 2000, all three Laureates presented high resolution structures of ribosomal subunits, Steitz of the large, Ramakrishnan and Yonath of the small ribosomal subunit.
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