Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. Any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of a number of eicosanoids, related to prostaglandin, that have a role in the clotting of blood

Etymologies

thromb(o)- + ox(o)- + -ane.
(American Heritage® Dictionary of the English Language, Fourth Edition)

Examples

  • It also reduces the production of an inflammatory prostaglandin messenger called thromboxane A2.

    Forever Young

  • "Aspirin works by preventing the production of a molecule called thromboxane, a naturally produced chemical that causes platelets to stick together and clot.

    TheDenverChannel.com - Local News

  • It is the irreversible blockade of platelet thromboxane synthesis that results in the inhibition of platelet aggregation.

    Aspirin: effects, poisoning

  • At appropriate doses, the drug lessens the formation of both prostaglandin and thromboxane-A but not the leukotrienes.

    Aspirin: effects, poisoning

  • They work by blocking the pro-inflammatory mediator thromboxane TXA-2 and not by blocking COX-1, which can result in gastric bleeding.

    Forever Young

  • It's little technical, but basically gives good reasons for why basically all women and men should take some form of fish oil: * An increased prostacyclin/thromboxane ratio induced by omega-3 FA can facilitate pregnancy in women with infertility problems by increasing uterine blood flow.

    Fish Oil & Fertility

  • Levels of arachidonic acid AA were higher in tumors from laboratory animals given MaxEPA, and levels of prostaglandin and thromboxane products of AA metabolism were reduced.

    The New Super-Nutrition

  • The prostaglandins and their related substances, which include the so-called stable prostaglandins as well as thromboxane and prostacyclin, can therefore best be characterized as local tissue hormones.

    Physiology or Medicine 1982 - Press Release

  • In 2009, correct responses were seen on light transmission aggregometry for 100% of cases of Glanzmann thrombasthenia and 95% of thromboxane generation defects.

    MedPageToday.com - medical news plus CME for physicians

  • Sugawara A, Uruno A, Kudo M, Ikeda Y, Sato K, et al. (2002) Transcription suppression of thromboxane receptor gene by peroxisome proliferator-activated receptor-╬│ via an interaction with Sp1 in vascular smooth muscle cells.

    PLoS ONE Alerts: New Articles

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