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from The American Heritage® Dictionary of the English Language, 4th Edition

  • adj. Both tonic and clonic. Used of a convulsion or muscular spasms.


Sorry, no etymologies found.


  • Gran or grand mal seizures -- also known as tonic-clonic seizures -- involve a loss of consciousness and violent muscle contractions.

  • Central nervous system effects are also common and can vary from agitation to tonic-clonic seizures.


  • All over the globe, according to this view, the same experience has been repeated: Some poor fellow suffers a generalized epileptic seizure—a “tonic-clonic seizure,” as it is now known to physicians.

    In the Valley of the Shadow

  • Jesse had generalized tonic-clonic seizures that lasted from one to two minutes.

    Knowing Jesse

  • Most often, though, they fall in a well-documented spectrum of mental and somatic anomalies, from the transient episodes of decreased awareness known as absence (formerly called "petit mal") to the tonic-clonic (or "grand mal") attack characterized by loss of consciousness, collapse and spasmodic stiffening and jerking.

    In the Grip of the Unknown

  • Webbing will be put on as I managed to flip/fall out of this chair during a grand mal/tonic-clonic.

    See me in the powerchair! Also postcards, packages, isolation and no GP

  • Phenytoin and fosphenytoin are used to control tonic-clonic grand mal and complex-partial seizures in epilepsy.

    Caution for Asians on epilepsy drug

  • Without medications, I suffer from grand-mal seizures also known as tonic-clonic seizures.

    I need a President Obama for medical reasons...I may die if McCain is elected

  • Do I believe the EMT and ER senior doctor who saw me have a series of three to four seizures and who I asked directly what it was, and was it “Pseudo” and he said “No, it was Atypical” meaning a seizure that is not a simple tonic-clonic and recommended Lyrica instead of the traditional drug until the exact seizure was found, along with Ativan and the Diazepam.

    The Neurologist: in brief

  • The tonic-clonic state or grand mal lasted approximately 2 minutes.

    The Neurologist: in brief


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