from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A polymerase that catalyzes the formation of RNA from a DNA template in the process of transcription.
- n. Reverse transcriptase.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A polymerase that catalyzes the transcription of DNA to RNA.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. the enzyme that copies DNA into RNA
Sorry, no etymologies found.
That was very simple — by using an enzyme that can read DNA and synthesise RNA, called a transcriptase, he added.
One example is reverse transcriptase, which is a viral enzyme involved in the infection of cells by telomeres.
Combining both protein and RNA components, telomerase is a reverse transcriptase which adds telomere DNA to the ends of molecules using an RNA template.
We had previously detected mouse mammary tumour virus (MMTV) sequences in the lymphocytes of breast cancer patients, and we were familiar with the technique of reverse transcriptase activity detection.
Furthermore, a member of this lab had been in our group teaching us the technique for the detection of reverse transcriptase, soon after the discovery of this enzyme by David Baltimore and Howard Temin.
This synthetic molecule, named HPA23, proved capable of inhibiting reverse transcriptase activity of Friend virus in culture.
My project analysed the use of a synthetic molecule which inhibited the reverse transcriptase to control leukaemia induced by Friend virus.
The cell culture supernatant was regularly tested for reverse transcriptase activity.
The first week of sampling did not show any reverse transcriptase activity, but in the second week I detected weak enzymatic activity, which increased significantly a few days later.
The reverse transcriptase activity level dropped dramatically however, as the T lymphocytes in the culture were dying.