“P.S. Did you know some folks, like one well known doc, took a bit of light olive oil before meals – like some do with ACV – to help him lose unwanted lbs.”
“Then I'm up, glass of water with lemon or dash of ACV, feed the cat, shower.”
“After reading your most enjoyable post a couple weeks ago, I decided to try my hand at making some ACV myself on a smaller scale.”
“The pathways for the formation of ACV-TP are shown in (Fig. 7).”
“However, the DNA polymerase of Epstein-Barr virus is exquisitely sensitive to the small amount of ACV-TP formed in EBV-infected cells (131).”
“The quantitative aspects of these differences in the amounts of ACV-TP formation and DNA polymerase inhibition (Ki value) by ACV-TP in virus-infected cells and uninfected cells are illustrated in Fig. 8 (123).”
“In addition, ACV-TP serves not only to inhibit, but also to inactivate, the viral DNA polymerase following the formation of the enzyme-template-acyclovir monophosphate complex (125).”
“Since the cellular thymidine kinase cannot use acyclovir as a substrate, very little ACV-TP is formed in uninfected cells (108), (119).”
“On the other hand, transfection of cells with a portion of the herpes virus genome containing the HSV thymidine kinase gene transforms normally resistant cells to ACV-sensitive cells (130).”
“Resistance to ACV may also result form mutations in the viral DNA polymerase (127,128,129).”
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