Creutzfeldt-Jakob disease

American Heritage® Dictionary of the English Language, Fourth Edition

1. n. A rare, usually fatal disease of the brain, characterized by progressive dementia and gradual loss of muscle control, that occurs most often in middle age and is caused by a slow virus. Also called Jakob-Creutzfeldt disease.

Wiktionary

1. n. pathology, neurology A rare, progressive, currently fatal disease of the nervous system, characterized by dementia and loss of muscle control. A prion disease, apparently transmissible from animals to humans by eating infected tissue, as well as from tissue interchanges among humans (corneal transplants, blood transfusions).