“Transient transfection luciferase reporter assays were carried out in duplicate, and repeated independently at least 3 times for 61 of 62 L1 ARORs before and after DHT exposure, and the results are displayed in a volcano plot (4A) which shows the fold change between DHT+ and DHT - luciferase levels and the p-value significance level by the Student's t-test.”
“For each construct, two independent transformants were measured in the DHT − condition and two in the DHT+ condition.”
“DHT is considered a forceful form of testosterone.”
“DHT is involved in the development of benign prostatic hyperplasia (BPH) and hair loss.”
“Researchers have long known that men who more readily convert the male hormone testosterone into a form called DHT have a higher risk of prostate cancer and are more likely to go bald.”
“Bernstein noted that the study's findings don't address genetic hair loss, in which a hormone called DHT causes hair follicles to shrink.”
“It does this by inhibiting the chemical (known as DHT) that is responsible for the destruction of hair cells when released from the scalp and hence allows the body to naturally regrow its hair without restriction.”
“DHT, which is the main cause of hair loss, binds to hair follicles, thereby restricting the ability of follicles to generate new and fully grown hair.”
“DR MESSENGER SAYS: 'Finasteride stops the conversion of testosterone to dihydrotestosterone, or DHT, which is thought to be the active hormone in hair loss.”
“Probably the weirdest are the Guevedoces males, who are XY but lack the 5-a-reductase enzyme which turns testosterone into DHT (a strong androgen responsible for differentiating the genitalia).”
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