Glycosylation

Figure F.2 Sugar Free Glycosylation happens when sugar molecules floating around in blood attach to protein molecules on the surface of cells—causingthose molecules to lose some of their function.

You Staying Young MEHMET C. OZ 2007

Figure F.2 Sugar Free Glycosylation happens when sugar molecules floating around in blood attach to protein molecules on the surface of cells—causingthose molecules to lose some of their function.

You Staying Young MEHMET C. OZ 2007

Figure F.2 Sugar Free Glycosylation happens when sugar molecules floating around in blood attach to protein molecules on the surface of cells—causingthose molecules to lose some of their function.

You Staying Young MEHMET C. OZ 2007

"There is a significant amount of interest in the medical community for a more effective treatment option for late-onset Pompe disease, and we believe, based on in vitro and in vivo nonclinical studies, that using our proprietary Glycosylation Independent Lysosomal Targeting, or GILT technology, BMN 701 has the potential to deliver more enzyme to lysosomes compared to traditional mannose-6-phosphate targeted approaches."

BioMarin Initiates Phase 1/2 Trial for BMN 701 for the Treatment of Pompe Disease - Yahoo! Finance 2011

Glycosylation of antibodies is typically either N-linked or O-linked.

FreshPatents.com: Notable Patent Applications - 07/22/2010 2010

Glycosylation, the addition of sugars to proteins, is a common posttranslational modification that is found on some 70% of human proteins.

News from The Scientist 2009

Fassbender K, Gulbins E, Liu Y, Rieschel M, et al. (2002) Glycosylation processing inhibition by castanospermine prevents experimental autoimmune encephalomyelitis by interference with IL-2 receptor signal transduction.

PLoS ONE Alerts: New Articles Alan Gillett et al. 2009

Glycosylation Is the Source of Many Aging-Related Problems

You Staying Young MEHMET C. OZ 2007

Glycosylation Is the Source of Many Aging-Related Problems

You Staying Young MEHMET C. OZ 2007

Glycosylation Is the Source of Many Aging-Related Problems

You Staying Young MEHMET C. OZ 2007