“At any rate, HGT is a mechanism for passing changes to offspring that arise for interactions with your environment.”
“Joy (1): No, HGT is a mechanism for altering genomes in already-living organisms.”
“No, HGT is a mechanism for altering genomes in already-living organisms.”
“An important stimulator of HGT is in fact, the SOS system.”
“Viral HGT is mediated by bacteriophage enzymes that insert the gene into the genome (normally for a prophage, but where it picks up genes and does it is a different story).”
“Nonetheless, what all this demonstrates, from antibacterial resistance to HGT, is far, far, far, from the "quirk" you portrayed the SOS system to be.”
“We do know that horizontal transfer happens naturally, but what we DON'T know about HGT is that it's "random.”
“It may be that organisms or proto-organisms such as viruses play a role in HGT events, but there is a fundimental randomness in that role.”
“As an example for how profound the notion of HGT has changed our thinking concerns the notion of the last universal common ancestor LUCA.”
“We will also be starting studies next year with products made in our own facility with enough human cell lines [ph] so that is now called HGT 1110.”
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