PCa

AR (A1675T) allele to early-onset and/or familial PCa in African Americans.

Naturejobs - All Jobs Si-Yi Hu 2010

Race, family history and age are the unequivocally accepted risk factors for prostate cancer (PCa).

Naturejobs - All Jobs Si-Yi Hu 2010

Not only can the LNCaP and C4-2 PCa progression model be applied for investigating androgen-refractory progression, but it can also be used to explore the development of radiation resistance in PCa.

Naturejobs - All Jobs Bang-Xiang Xie 2010

We identified a germline AR (A1675T) (T559S) substitution mutation in the DNA-binding domain in three PCa-affected members of an African-American family with a history of early-onset disease.

Naturejobs - All Jobs Si-Yi Hu 2010

AR germline mutation in an African-American family with a history of familial PCa.

Naturejobs - All Jobs Si-Yi Hu 2010

AR in association with familial PCa in African Americans who have a higher incidence and mortality rate and a clinically more aggressive disease presentation than Caucasians.

Naturejobs - All Jobs Si-Yi Hu 2010

G-1 inhibited the growth of androgen-dependent and androgen-independent prostate cancer (PCa) cells in vitro and PC-3 xenografts in vivo.

Naturejobs - All Jobs Q K Y Chan 2010

Some cancer lines (VCaP, DuCaP, NCI-H660 and MDA-PCa 2b) failed to form spheroids, but persisted as single cells ( "single" or "singular phenotype") for up to 2 weeks.

PLoS ONE Alerts: New Articles Ville Härmä et al. 2010

The discovery of this signaling pathway lays the foundation for future development of GPR30-based therapies for PCa.

Naturejobs - All Jobs Q K Y Chan 2010

Genomic DNAs of 60 patients from 30 high-risk African American and Caucasian families participating in the Louisiana State University Health Sciences Center genetic linkage study of PCa were studied.

Naturejobs - All Jobs Si-Yi Hu 2010