GNU Webster's 1913
- n. one of several antibiotic substances produced by several species of Streptomyces, active against various fungi. They are used only experimentally, not in medicine. The two best-known antimycins are antimycin A1 (C28H40N2O9) and antimycin A3 (C26H36N2O9). They are notable for their mechanism of action, interference with the proton pumping mechanism of fungi.
- n. a crystalline antibiotic active against various fungi
“Those studies found that the protein encoded by the Ciona AOX gene made its way to mitochondria, where it conferred cyanide-resistant respiration and protected against metabolic acidosis, oxidative stress, and cell death when cells were treated with OXPHOS inhibitors such as antimycin or cyanide.”
“Rather, Rounds showed, by treating pollen tubes with growth inhibitors including cyanide, oligomycin and antimycin-A, that pollen tubes can withstand such toxins and after an adjustment period will begin to grow again but at a slower rate while still exhibiting growth oscillations described above.”
“Quite the contrary, mitochondria taken from AOX-expressing flies showed significant resistance to cyanide, and the flies partially resisted both cyanide and antimycin.”
“(, 1 mM, 27% loss of activity )  NADP+ (, competitive )  antimycin A”
“(enzyme of intact mitochondria )  antimycin A < 1, 2, 7 >”
“(competitive inhibitor with respect to 2-oxoglutarate, noncompetitive with respect to Fe2+ )  antimycin A”
These user-created lists contain the word ‘antimycin’.
It's a hazardous world out there...poison all around. I've tried not to include too many drugs (including medicines) and have ignored the fact that too much of anything can poison you. We're going ...
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