Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology A phagosome in which part of a cell's own cytoplasm is digested

Etymologies

Sorry, no etymologies found.

Support

Help support Wordnik (and make this page ad-free) by adopting the word autophagosome.

Examples

  • The parental macronucleus is engulfed by a large autophagosome, in which many mitochondria that have lost their membrane potential are incorporated.

    BioMed Central - Latest articles Takahiko Akematsu 2010

  • Yoshimoto K, Ohsumi Y, Jeon JS, An G (2009) OsATG10b, an autophagosome component, is needed for cell survival against oxidative stresses in rice.

    PLoS ONE Alerts: New Articles Fengxia Liu et al. 2010

  • Although LC3 is currently thought to function primarily in the cytosol, the site of autophagosome formation, EGFP-LC3 often appears to be enriched in the nucleoplasm relative to the cytoplasm in published fluorescence images.

    Elites TV PLoS ONE 2010

  • The autophagosome fuses with the lytic lysosome to form autophagolysosomes that degrades engulfed molecules

    PLoS ONE Alerts: New Articles Susu Zughaier et al. 2010

  • Since bafilomycin A1 inhibits the degradation of autophagosomes, the levels of LC3-II in bafilomycin A1-treated cells reflect the rate of autophagosome formation

    PLoS ONE Alerts: New Articles Bing Wang et al. 2010

  • Induction of autophagy led to a visible decrease in levels of soluble EGFP-LC3 relative to autophagosome-bound protein, but had only modest effects on the nucleo-cytoplasmic ratio or diffusional mobility of the remaining soluble pools of EGFP-LC3.

    Elites TV PLoS ONE 2010

  • The autophagosome fuses with the lytic lysosome to form autophagolysosomes that degrades engulfed molecules

    PLoS ONE Alerts: New Articles Susu Zughaier et al. 2010

  • Mizushima N, Ueno T, Yamamoto A, Kirisako T, et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

    PLoS ONE Alerts: New Articles Susu Zughaier et al. 2010

  • The parental macronucleus is engulfed by a large autophagosome, in which many mitochondria that have lost their membrane potential are incorporated.

    BioMed Central - Latest articles Takahiko Akematsu 2010

  • Mizushima N, Ueno T, Yamamoto A, Kirisako T, et al. (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

    PLoS ONE Alerts: New Articles Susu Zughaier et al. 2010

Comments

Log in or sign up to get involved in the conversation. It's quick and easy.